The year is 1921, and 'Nobody' Alice James is on a cross-country train, carrying a bullet wound and fleeing for her life following an illicit drug and liquor deal gone horribly wrong. Desperate to get as far away as possible from New York City and those who want her dead, she has her sights set on Oregon: a distant frontier that seems the end of the line. She befriends Max, a black Pullman porter who reminds her achingly of Harlem, who leads Alice to the Paragon Hotel upon arrival in Portland. Her unlikely sanctuary turns out to be the only all-black hotel in the city, and its lodgers seem unduly terrified of a white woman on the premises. But as she meets the churlish Dr. Pendleton, the stately Mavereen, and the unforgettable club chanteuse Blossom Fontaine, she begins to understand the reason for their dread. The Ku Klux Klan has arrived in Portland in fearful numbers - burning crosses, inciting violence, electing officials, and brutalising blacks. And only Alice, along with her new